Which amphetamine-like drug potentiates the action of CNS stimulants and is prescribed for narcolepsy?

Which amphetamine-like drug potentiates the action of CNS stimulants and is prescribed for narcolepsy?

• A. Modafinil
• B. Methylphenidate
• C. Bupropion
• D. Atomoxetine

Answer: (B)

The correct answer is methylphenidate, which is commonly prescribed for attention-deficit hyperactivity disorder (ADHD) and narcolepsy. Methylphenidate works by increasing the levels of certain neurotransmitters in the brain, particularly dopamine and norepinephrine. This action stimulates the central nervous system, enhancing wakefulness and alertness, making it effective for treating conditions characterized by excessive daytime sleepiness, such as narcolepsy. Methylphenidate is classified as an amphetamine-like stimulant, which means it shares some structural and functional similarities with amphetamines, particularly regarding their effects on neurotransmitter release and reuptake inhibition. This property contributes to its ability to enhance the efficacy of other CNS stimulants when used in conjunction. Modafinil, while used for narcolepsy, has a different mechanism of action, primarily involving the modulation of neurotransmitters like hypocretins and is not classified as an amphetamine. Bupropion is primarily an antidepressant that acts on norepinephrine and dopamine and is not specifically classified as a stimulant or used for narcolepsy management. Atomoxetine is a selective norepinephrine reuptake inhibitor, used primarily for ADHD but not classified as a stimulant and not typically prescribed

The correct answer is methylphenidate, which is commonly prescribed for attention-deficit hyperactivity disorder (ADHD) and narcolepsy. Methylphenidate works by increasing the levels of certain neurotransmitters in the brain, particularly dopamine and norepinephrine. This action stimulates the central nervous system, enhancing wakefulness and alertness, making it effective for treating conditions characterized by excessive daytime sleepiness, such as narcolepsy.

Methylphenidate is classified as an amphetamine-like stimulant, which means it shares some structural and functional similarities with amphetamines, particularly regarding their effects on neurotransmitter release and reuptake inhibition. This property contributes to its ability to enhance the efficacy of other CNS stimulants when used in conjunction.

Modafinil, while used for narcolepsy, has a different mechanism of action, primarily involving the modulation of neurotransmitters like hypocretins and is not classified as an amphetamine. Bupropion is primarily an antidepressant that acts on norepinephrine and dopamine and is not specifically classified as a stimulant or used for narcolepsy management. Atomoxetine is a selective norepinephrine reuptake inhibitor, used primarily for ADHD but not classified as a stimulant and not typically prescribed